"Understanding Resistance to Tuberculosis"
Dr. Barry Bloom

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CHAPTER POINTS:

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  1. Introduction: Why study TB?
  2. The Challenge of TB: Who Lives, Who Dies?
  3. Epidemiology of TB in the U.S.
  4. An Exposed Individual’s Likelihood of Disease
  5. Immunological Research Questions
  6. Role of Adaptive Immunity in Fighting TB
  7. Searching for Essential Immune Response Components: T-Cell Response
  8. Searching for Essential Immune Response Components: Microbiocidal Mechanisms
  9. Efficacy of BCG Vaccine in International Trials
  10. Searching for Essential Immune Response Components: Cytotoxic T-cells
  11. Searching for Essential Immune Response Components: Role of Innate Immunity
  12. Research on the Innate Response to TB in Mouse versus Human Models
  13. DNA Microarray Research Reveals Function of Vitamin D Receptor in the Human Response
  14. Clinical Significance of the Role of the Vitamin D Receptor in the Humane Immune Response to TB
  15. Vitamin D in Human Medical and Evolutionary History
  16. Is Vitamin D Involved in General Human Antimicrobial and Anticancer Response?
  17. What Dr. Bloom’s Vitamin D Receptor Model Explains and Suggests