Immunology
Scientist Lecture Videos
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"The Role of Innate & Adaptive Immunity in the Response
to Pathogens"
Dr. Michael Carroll
Professor of Pediatrics & (Pathology) Harvard Medical
School,
The CBR Institute for Biomedical Research
Dr. Carroll will describe basic concepts in innate and adaptive immunity and
how the two systems work synergistically. His discuss will focus on a murine
model in which the innate immune system enhances the antibody response to an
infectious viral agent (herpes simplex virus).
"T-cell responses to Microbial Pathogens"
Dr. Michael Starnbach
Department of Microbiology and Molecular Genetics,
Harvard
Medical School
Bacterial pathogens have devised a great number of virulence strategies that
allow them to successfully use animal hosts to replicate and spread. These
strategies also dictate the types of immune responses that are effective at
eliminating these organisms. The lecture will focus on how the adaptive immune
system responds to bacterial pathogens.
"Harnessing RNA Interference for Therapy"
Dr. Judy Lieberman
Senior Investigator and Professor of Pediatrics,
The CBR
Institute for Biomedical Research, Harvard Medical School
RNA interference is a recently described process for silencing gene expression
that occurs in all cells. RNA interference uses small double stranded RNAs
to target messenger RNAs with homologous sequences for degradation. Dr. Lieberman
will discuss how these small RNAs might be used as drugs to treat a variety
of human diseases.
"Innate Immunity in Tropical Disease"
Dr. Donald Harn
Professor, Department of Immunology and Infectious Diseases,
Harvard School of Public Health
Dr. Harn will discuss the activation of "immune" cells by a family
of oligosaccharides that are expressed on a variety of pathogen surfaces, including
the human helminth parasite Schistosoma mansoni. The role of toll-like receptors
in immune responses to tropical parasites, and the development of vaccines
for infectious diseases of the tropics will also be explored.
"Co-option and Destruction of the Immune System by HIV"
Dr. Robert Lue
Dean of the Harvard Summer School,
Senior Lecturer on Molecular
and Cellular Biology,
Director of HHMI Undergraduate & Outreach Programs at Harvard
Conservative estimates indicate that more than 40 million men, women, and
children are currently infected with HIV world-wide. The vast majority of these
individuals will go on to develop AIDS and become part of the most serious
medical crisis in recorded history. Dr. Lue will discuss the diverse ways in
which the virus and viral proteins both co-opt and ultimately destroy the human
immune system.
"Differentiation and Function of CD4"
Dr. Laurie Glimcher
Higgins Professor of Biochemistry,
Department of Molecular and Cellular Biology
"Natural Killer Cells"
Dr. Jack Strominger
Higgins Professor of Biochemistry,
Department of Molecular and Cellular Biology
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